NTA appears to be more convenient to use, but still has certain drawbacks: for example, two populations can only be resolved if their particle diameters differ at least by a factor 1.5. It was argued that EM underestimates the size of vesicles in addition, the real size distribution of the entire vesicle population is not assessable by this method. Several other techniques were tested in the past for size determination of EVs isolated from blood, for example scanning or transmission electron microscopy (EM) nanoparticle tracking analysis (NTA), and flow cytometry (FC). However, further development of the methodology is required. These results show that SLS and DLS are promising methods for the analysis of morphological features of ENPs and have the potential to discriminate between OC and BP patients. The R h and R g of ENPs in BP patients were larger than in OC patients, with ρ ≈ 1.1–2, implying a more elongated/distorted shape. The shape parameter ρ of both particle populations was around 1, which is typical for spherical particles with mass concentrated on the rim, as in vesicles. In thawed samples, larger particles ( R h mostly above 100 nm) were detected as well. R h and R g of the predominant ENP population of OC patients were in the range 20–30 nm (diameter 40–60 nm). The hydrodynamic radius ( R h) and the radius of gyration ( R g) of ENPs were calculated from the angular dependency of LS intensity for two ENP subpopulations. Samples of plasma and ascites (OC patients) or plasma, peritoneal fluid, and peritoneal washing (BP patients) were analyzed. In this contribution, the use of non-invasive static (SLS) and dynamic light scattering (DLS) for the characterization of extracellular nanoparticles (ENPs) in body fluids of advanced serous ovarian cancer (OC) and benign gynecological pathology (BP) patients is demonstrated and critically evaluated. In parallel to medical treatment of ovarian cancer, methods for the early detection of cancer tumors are being sought.
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The investigation at Unit 1 aims to measure the melted fuel mounds, map them in three dimensions, analyze isotopes and their radioactivity, and collect samples, TEPCO officials said. TEPCO said it will conduct additional probes after analyzing the data and images collected by the first robot.įive other robots, co-developed by Hitachi-GE Nuclear Energy and the International Research Institute for Nuclear Decommissioning, a government-funded consortium, will be used in the investigation over the next several months. The fuel at Unit 1 is submerged in highly radioactive water as deep as 2 meters (6.5 feet). The robot probe of the Unit 1 reactor began Tuesday and was the first since 2017, when an earlier robot failed to obtain any images of melted fuel because of the extremely high radiation and interior structural damage. The annual exposure limit for plant workers is set at 50 millisievert. Takahara said further probes will be needed to confirm the objects in the images.Īt one location, the robot measured a radiation level of 2 sievert, which is fatal for humans, Takahara said. TEPCO spokesperson Kenichi Takahara said the piles of debris rose from the bottom of the container, including some inside the pedestal - a structure directly beneath the core - suggesting the mounds were melted fuel that fell in the area. Oil drilling in Gulf safer, but concerns linger, report says Its removal is a daunting task that officials say will take 30-40 years. Most of their highly radioactive fuel fell to the bottom of their containment vessels, making its removal extremely difficult.Ī previous attempt to send a small robot with cameras into the Unit 1 reactor failed, but images captured this week by a ROV-A robot show broken structures, pipes and mounds of what appears to be melted fuel and other debris submerged in cooling water, plant operator Tokyo Electric Power Company Holdings said Thursday.Ībout 900 tons of melted nuclear fuel remain inside the plant’s three damaged reactors, including about 280 tons in Unit 1. TOKYO (AP) - A remote-controlled robot has captured images of what appears to be mounds of nuclear fuel that melted and fell to the bottom of the most damaged reactor at Japan’s wrecked Fukushima nuclear plant, officials said Thursday.Ī massive earthquake and tsunami in 2011 damaged cooling systems at the power plant, causing the meltdown of three reactor cores. Note: This chapter is a revised version of a blog post titled, “ Designing Your eBook: Choosing Between Affinity Publisher and Adobe InDesign,” on The Netizen Praxis. ” If you’re looking to create a fixed-layout EPUB, Concepción offers “ InDesign: Creating Fixed-Layout EPUBs.” Even though Apple named Affinity Publisher as one of the best apps, I’ll stay with Adobe InDesign for my eBook publishing ventures. For help with reflowable EPUBs, check out “ InDesign CC to EPUB. Additionally, Ann-Marie Concepción, who I mentioned at the beginning of this article, offers two LinkedIn learning videos related to publishing eBooks with Adobe InDesign that go beyond her “Ebook Foundations” course. While the price difference between the two software is tempting, I like the idea of being able to start my layout with a predesigned template. Whether you decide to use Affinity Publisher or Adobe InDesign depends on your design capabilities and whether you intend to publish eBooks using only the PDF format. InDesign users can choose from several free and paid eBook templates at Adobe Stock. Cousins’ article does not mention if you can open Affinity Publisher files in Adobe InDesign, and I found no information indicating that you can.Īffinity Publisher costs a flat fee of $49.99 to download, whereas Adobe InDesign is subscription-based and starts at $20.99 per month.Īffinity Publisher lacks the document setup presets found in Adobe InDesign, and there are no predesigned templates to choose from. You can open Adobe InDesign files in Affinity Publisher so long as the file has the IDML extension. Here are few things Cousins mentions in her article: Bookemon - A variety of thematic book templates Affinity Publisher - Low-cost. Differences between Affinity Publisher and Adobe InDesignĬarrie Cousins, the chief writer at Design Shack, posted the article, “ What Is Affinity Publisher? a 101 Intro (+ vs. Free book design software and online creators for print and eBooks. Both programs allow you to design layouts for print and digital media, and the software operates on Windows and Mac computers. As I mentioned, the software has a similar function to Adobe InDesign. Serif Ltd., a British software development and publishing company, launched Affinity Publisher in June of 2019. When Concepción’ recorded her training - the course was released SeptemAffinity Publisher was not yet available. 4/17/2023 0 Comments Neck diagrams file .fdbfbd file by following this little tutorial: How to share Neck Diagrams. fbd diagram page file which'll then allow others to download and open your page in their copies of Neck Diagrams You can get a copy of the. Though it is able to render the ER diagram directly from the databaseĪnd not just only from the ER markup language. Another thing you could do is attach the actual. Owned by a user named postgres with a password of postgres. Find your way around the guitar neck and fretboard notes, on acoustic and electric guitars. Postgres database with a schema named test in a database named test all Guitar Neck Diagrams Freeware Guitar Fretboard Notes v.1.0.0 Free ebook for finding guitar notes and fret positions, making guitar music easier to play. .fdb files neck diagrams free Today, steel is one of the most common manmade materials in the world, with more than 1.6 billion tons produced annually. Thanks to it’s modular architecture, it can be connected to other There are also diagrams that show nice combinations of both, along with the circles that represent guitar scale patterns. Installs hooks/patches the running process. $ eralchemy -i 'markdown_file.er' -o erd_from_markdown_file.pdf From a Postgresql DB to a markdown file excluding tables named temp and audit $ eralchemy -i -o filtered.er -exclude-tables temp audit From a Postgresql DB to a markdown file excluding columns named created_at and updated_at from all tables $ eralchemy -i -o filtered.er -exclude-columns created_at updated_at From a Postgresql DB to a markdown file for the schema schema $ eralchemy -i -s schema Usage from Python from eralchemy import render_er # Draw from SQLAlchemy base render_er ( Base, 'erd_from_sqlalchemy.png' ) # Draw from database render_er ( "sqlite:///relative/path/to/db.db", 'erd_from_sqlite.png' ) Architecture fdb files neck diagrams windows Loadable Kernel Modules (or LKMs) are pieces of code that can be loaded and unloaded into the kernel upon demand.ound malicious artifacts related to '211.1.230.194'. Usage from Command Line From a database $ eralchemy -i sqlite:///relative/path/to/db.db -o erd_from_sqlite.pdfĭatabase url. Neck Diagrams is the BEST, the most FLEXIBLE software youll find to create great fretboard diagrams. Both are available for Windows, Mac and Linux. create a database named test.fdband store it in a directory named dataon your Ddrive: SQL>CREATE DATABASE 'D:\data\test. To install ERAlchemy, just do: $ pip install eralchemy Homebrew $ brew install eralchemy Install The simplest way to install eralchemy on OSX is by using Here are some free Guitar Fretboard Diagram generator websites as well as desktop software that you can use to create guitar fretboard or fingerboard diagrams on your Windows 11/10 PC: Guitar. ExampleĮxample for NewsMeme Quick Start Install on a mac ERAlchemy generates Entity Relation (ER) diagram (like the one below)įrom databases or from SQLAlchemy models. RMID), and MUS tunes (as used by Id Software in numerous games like Doom, Heretic, Hexen, etc). It plays standard MIDI files, as well as MIDI in RIFF (ie. Inappropriate trivia: the IRQ check routine that always fails wasn't done by Sierra but just copied from Creative Labs' very first Sound Blaster SDK.įRP.SX has the sound resources modified so that PCM tracks are included in the and track lists as well.ĭOSMid is a text mode MIDI and MUS player for DOS that can run on a 8086 CPU. SX.OVL includes an AUDBLAST.DRV that doesn't fail to initialize on faster machines. The modification could be done more elegantly right now it is forced to always load AUDBLAST.DRV, no matter the setting. KRONDOR.EXE had to be modified so that it even bothers to call up AUDBLAST.DRV with any RESOURCE.CFG entry other than SNDBLAST.DRV. Patch to play General MIDI sound along with PCM samples. Thanks for the updated version of the driver. I also tried it with SQ3 and it seems to work fine there as well. I got no static when knocking on the witch house door if you still do, report. Since in this game all PCM sound effects sound different from their respective MIDI data, no selectivity is needed. I've increased the SB initialization timeout in MTBLAST.DRV to where there should be no problem at 10000 cycles and even higher, so I hope that resolves the speed issue. If you subsequently want to switch to the MT32.DRV or SNDBLAST.DRV drivers then delete the separate SOUND.* files. Extract the archive into the game directory and make sure soundDrv=MTBLAST.DRV is in the RESOURCE.CFG file. I'll let those more familiar with the game than myself decide if it's fully working or not. MT-32 music with SB sfx seems to be working in QFG2 version 1.102 and 1.105 with the attached patch. This driver corrects problems with some high-resolution Sierra games that support both MT-32 and DAC playback. Comments on whether it does are appreciated. In theory, it should work will all language versions. APPLY.BAT must only be run once to modify MONKEY2.001 in the manner described then it can be deleted. In addition, APPLY.BAT fixes the programming mistake that the barkeep's spitting sound is only heard on AdLib. REORDER.COM simply reorders them so that the PCM one appears first in the file. The reason is that these exist for PCM, AdLib and Roland, but MONKEY2.EXE will give the Roland file to the sound driver because that one appears first in MONKEY2.001. Replacing ROLAND.IMS would have been the more logical option, but unfortunately, the game's script code knows what the selection is and will not even bother to try to play Largo's "whoa!" sound effects with any selection other than Sound Blaster, so it is this driver that has to be replaced.ĪPPLY.BAT must be run once in order to hear all PCM "spitting" sound effects. SOUNBLAS.IMS replaces the original SOUNBLAS.IMS, so you have to run the game with "MONKEY2 s". Until now.Īttached find a patch that allows for Roland MT-32 music together with PCM sound effects for the Sound Blaster, and AdLib sound effects when they are the only ones available. If you want both, you are forced to use ScummVM, which in my opinion seriously breaks the whole retrogaming experience (and its OPL2 emulation is hideous IMHO). Monkey Island 2 has great music with a Roland MT-32 however, most sound effects can only be heard with the AdLib or Sound Blaster selection. To install for DOS, extract MI1_Ultimate_Talkie_Edition_1.02.zip and put the MI1_Ultimate_Talkie_Edition_Builder folder where you have Monkey1.pak installed.ģ) Run install.bat and wait for the MI1 Ultimate Talkie Edition to be created. You also need a copy of xWMAEncode.exe (not included here for legal reasons).ġ) Put xWMAEncode.exe inside the tools subfolder. 1 GB of temporary disk space, 194 MB for DOS, 825 MB for FLAC and 168 MB for Ogg Vorbis version. To get this working, you need a copy of Monkey Island Special Edition PC version installed, approx. Music support added for MT-32, General MIDI and Ad Lib. Ultimate "Talkie" Edition - this builds a talkie version for DOS and ScummVM out of the SE version. Also available here are the original user manuals for lots of the hardware. Roland MT-32, as well as General MIDI (Roland SC-55, etc). There are game patches to help MIDI sound modes work in games, or play better when combined with OPL2/3 sound effects, plus DOS and Windows utilities and applications that can be used for both pre-General MIDI, e.g. These downloads are all MIDI-related or "pre-MIDI" sample sound-related. 4/17/2023 0 Comments Solveig mp3 trimmerSupports of MKV, AVI, MP4, WEBM files editing with multiple audio tracks. Cut AVI, MPEG-2, WMV, MP3, AVCHD, FLV, MP4, MOV, WEBM, and MKV files loaded to Windows Media Player. The plugin saves and edit any movie/video clip or musical/audio track loaded in Windows Media Player. Recommendation: Joyoshare VidiKit Lossless Quality 1 Free MP3 Cutter. Media files merging for all supported formatsįile slicing by parts, duration or file size. SolveigMM WMP Trimmer Plugin Home Edition. Here we introduce 9 best free MP3 cutter for both Windows and Mac users to cut any MP3 files in an easy way. Overview of SolveigMM WMP Trimmer Plugin Business Edition 3 This plugin is the popular tool that turns the well-known Windows Media Player into a multimedia editor. Here we introduce 9 best free MP3 cutter for both Windows and Mac users to cut any MP3 files in an easy way. Supports editing of external subtitles for AVI, MKV, WEBM, MP4 of ASS, SRT formatsĬut commercials: simultaneously delete multiple parts of a movie remove all ads from a movie with just two actions.īatch mode editing: unlimited editing tasks can be done in one run (in the Business version)Ĭommand line interface to accept XML file with a batch tasks description(in the Business version) Supports editing of embedded subtitles for AVI, MKV, WEBM files of UTF8, ASS, SSA, GAB2 formats SolveigMM WMP Trimmer Plugin Home Edition on the other hand, attaches itself to Windows Media Player so you can split songs and videos into multiple parts on the fly. SolveigMM WMP Trimmer plug-in is a fast and small tool to cut without loss AVI, WMV, ASF, WAV, WMA, MP3, MPEG-2, MPEG-1, AVCHD, FLV, MP4, MOV, WEBM and MKV files loaded to Windows Media Player. ts ), MP4 (.mp4), MOV (.mov), MKV (.mkv), WebM (.webm), FLV (.flv), AVI (.avi), Windows Media files (.asf. Smart editing approach to keep 99 percents of input data in original way It is capable of cutting out any number of video or audio fragments at once, without re-encoding the data, preserving the original quality of the movie. The editor builds on the frame-accurate approach keeping 99.9% of data intact. The software provides seamless editing experience, removing unwanted video parts with just a few clicks, perfectly cutting and joining video and audio streams. SolveigMM Video Splitter is a video editor that operates with FLV, AVC/H264, MP4, MOV, AVCHD, MPEG-2, MKV, WEBM, MPEG-1, AVI, WMV, MP3, WMA files. Folders disappeared in outlook 2013, Asus n551jk cn157h review, Cutting beer bottles with. 4/17/2023 0 Comments Walmart norton antivirusFake gift card activation websites and phone numbers.Scammers sticking fake barcodes on the backs of gift cards.Imposters demanding gift card payments over the phone.The 11 Latest Gift Card Scams (and How To Avoid Them) Try Aura’s award-winning identity theft protection solution free for 14 days and safeguard yourself against scammers. ✅ Take action: If scammers have your personal information (even just your name and phone number), your bank account and identity could be at risk. The moment someone asks for a gift card payment, you should hang up or delete the email. Legitimate companies will never demand (nor typically accept) payment via gift cards. The bottom line: If you’re told to pay with gift cards, it’s a scam. This information is typically on the back of the card, and it gives them instant access to the money on the card.
– You do not need to be online to use WordWeb – Among the many new words in this version you’ll find everything from snowflakery to spaffing, headcam to nanoplastic. – Improve mouse wheel and trackpad scrolling control – Support for Dark Mode theme (WordWeb and additional non-web dictionaries) – Now over 300,000 words in the word list, about 10,000 more compared to version 8 – Links to phrasal verb and compounds for each word – Much more comprehensive tagging of informal and other usages – Extensive revisions, with thousands of new words, senses, updates and clarifications – Includes many names of places and people, with a concise definitions and related words. You can also copy to the clipboard parts of definitions, all of the definitions, the selected related word, or all of the listed related words (or anagrams/words matching a pattern). – If you are looking up a word from a document you are editing, you can select any word and press the “Replace” button to substitute a synonym. You can also export the list to a text editor, delete items, or delete the entire history list. WordWeb also builds a list words you’ve looked up, so you can go back and check you remember definitions. There’s a feature to randomly look one up as a way of helping you remember vocabulary. – Use the bookmark feature to remember useful words. You can also import and export to common spreadsheet-format files. – Select “New Definition” from the “Edit” menu to add a new word (or set of words) with definition. How many words can you make using the letters in “constitutional”? WordWeb Pro’s answer: 726! – Enter a word and you can find all straight and multiple word anagrams. For example search for “female fox” and it will find the definition of “vixen”. – Use the “full text” button to search for text appearing in any definition. The screenshot shows what you’d get if you did a punctuation sensitive search in the optional “Compounds and Phrases” word list for phrases ending in “word”. You can also search a wide range of optional extra word lists using the Find Word window. – Using the “Find Word” feature you can quickly find words matching a pattern. – You can add your own technical glossaries (or list of company acronyms, etc) using the option on the “Glossaries” menu. – You can also get optional third-party dictionaries, including the Oxford, Chambers and Collins dictionaries, shown on separate tabs like the web references. To look at a particular sense you can click on the sense number. – If you are looking for a particular part of speech you can click on the Noun, Verb, Adjective or Adverb buttons to show only the relevant synonyms and related words. Wikipedia and some online dictionaries are installed by default. The list of tabs can be customized to use your favorite references. Each reference is on a separate tabbed page for easy cross-referencing. – In addition to using the comprehensive English dictionary and thesaurus supplied, if you are online you can also search your choice of web references. – Add Oxford, Chambers and Collins dictionaries – Quickly cross-reference Wikipedia and others – Definitions, synonyms and related words – One-click lookup in any Windows program – Offline English dictionary and thesaurus WordWeb has the option to highlight widely used synonyms, great for helping you write clear easy-to-understand English. If you are editing a document you can select a synonym and replace the look-up word. The hotkey can be customized, or you can use a keyboard shortcut if you prefer. If you are online, with one extra click you can also search web references, for example Wikipedia. WordWeb Pro can look up words in virtually any program with just one click: just hold down the Ctrl key and right-click on the word. 4/16/2023 0 Comments Drug dealer simulator xboxQuickly rising to the top of the narco-game game, Wildlands is the first Ghost Recon we’ve seen that entrenches you so heavily in the drug-trade. Mario (we’d like to see where he got that medical degree) genuinely looks like he’s tripping balls throughout this classic Nintendo game, and we can only assume the creators of this game had gotten high on their own supply when they commit to this game. Would you really want a guy who’s been eating shrooms for years to prescribe you pills? Dr. Big (yup, seriously) made Narc a standout for its time. The fact that the two heroes were named Max Force and Hit Man and were out to dethrone Mr. The fact that you were intended to confiscate money from the drug-addicts you were tasked to arrest and/or kill only fueled that fire. Two-man, arcade-style drugee killing was the hallmark of 1988’s Narc, followed shortly by public outcry against the game. Army-issued morphine plays a suspect role, brings us back to the glory days of narcotics, where an unsuspecting FDA was still in the process of realizing that opium-products needed at least a bit of regulation. LA Noire dealt with all the crime in LA in the ’40s, so obviously you’re going to get mixed up with heroin. We’ll never know why Activision pulled the plug on this series after two successful outings in LA and NYC. True Crime’s “high” points were its voice actors which included the likes of Mickey Rourke and Laurence Fishburne. When you’re the son of a criminal kingpin making a go of it as an undercover detective in the PDNY (their similarities to the NYPD are astounding) then it’s not a matter of if you’ll encounter the underground drug trade of a major metropolis, it’s a matter of when. The fact that the ultimate goal of the game was to take down a drug kingpin named Pit Bull (no relation) makes it all the better. It wasn’t the most original plot, but it was unique for its time and an interesting take back in the NES days. Originally called “Drug Czar,” the entire point of Raid 2020 was to defeat drug dealers, straight up. Max is one of the few characters who straddles the line between narcotic user and crusader… which probably explains all that slo-mo bullet time in his games. When you’ve been entrenched in the underworld, spent years of your life chasing down a designer drug syndicate and seen as much violence and tragedy as Max Payne, there’s no real surprise that our hero started popping pills. No matter how it shakes down, Tripto fucks with Norman like one of those before/after meth pictures. In many ways, Heavy Rain’s drug of choice actually sounds more like methadone, a drug to get you off harder drugs. Unlike most other games on this list, it’s Heavy Rain’s hero, Norman, who is indulging in the fictional Tripto’s habit. Or so we’re led to believe in Heavy Rain. It’s as simple game that was as addictive as the drugs we were selling in it. Highest profit after paying back the loans wins. That means borrowing capital from loan sharks to buy up and sling as many drugs as you can in a 30-day span. You may have played Dope Wars on your computer, your phone, or even your TI-83 calculator when you were pretending to learn trigonometry in middle school because it’s a text-based game that challenges you to channel your inner drug kingpin. 4/16/2023 0 Comments Skyrim skeditThe world offers up a vast array of activities and quests, along with skills to master and different fighting styles to try out. You must help him regain his memories and save Hyrule. Link awakens from a 100-year long sleep to a Hyrule he doesn’t know or remember. The freedom to explore and go about your journey at your own pace is one of the best things about Skyrim, and Legend of Zelda: Breath of the Wild does just that in an enchanting Link-shaped package. It has plenty of intrigue and mystery, and the variety of foes you face keeps it exciting and fresh. The combat is not unlike Skyrim's, with specializations to choose from and skillsets to advance. In its fantastical setting of Gransys Island, you’ll traverse through dangerous dungeons and face many different monsters of all shapes and sizes - so if you’re already missing the dragon fights, Dragon’s Dogma can fill that need.Īnd if you’re someone who loves spending hours crafting your character, you’ll be glad to know there are lots of character creation customization options to help you nail the look of your Arisen. You take on the role of the Arisen, a character whose heart is stolen by a dragon and gets resurrected to defeat the very same beast. Dragon’s Dogma: Dark ArisenĬapcom’s open-world action-adventure has one very obvious thing in common with Skyrim: dragons. There are endless hours of adventuring to be had. Sound familiar? If you’ve been sitting on this one, the Game of the Year Edition includes the excellent Blood and Wine and Hearts of Stone DLCs, which gives you oodles of additional gameplay. Honestly, there’s so much to do and discover, you can easily wind up spending hours exploring the vast landscapes without touching the main story-line. The scope and depth of the Witcher 3 makes for one unforgettable experience, with fantastical beast battles and gorgeous vistas to soak up. Much like Skyrim, you can decide how you play out your adventure in its rich world fit to bursting with story-driven quests and areas to explore. In the race find her before the Wild Hunt, you'll be thrown into monster fights, political unrest, and so much more besides. In the shoes of monster-slayer Geralt of Rivia, you’re tasked with finding Ciri who happens to be the heir to the Cintra throne. As one of the best fantasy RPGs in recent memory, The Witcher 3: Wild Hunt is an absolute must. |
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